of TauroLock™ lock solutions
- TauroLock™ has proven effective against a wide range of bacteria and fungi (including MRSA and VRE).
- TauroLock™ is not an antibiotic – no bacterial resistance has been observed.
- TauroLock™ prevents the colonisation of catheters at the planktonic level and the development of biofilm within catheters.
“In vitro, the antimicrobial agent taurolidine inhibited virtually all of the bacteria tested, including vancomycin-resistant enterococci, oxacillin-resistant staphylococci, and Stenotrophomonas maltophilia, at concentrations between 250 and 2,000 mg/ml. Taurolidine was not effective in experimental endocarditis. While it appears unlikely that this antimicrobial would be useful for systemic therapy, its bactericidal activity and the resistance rates found (<10-9) are favorable indicators for its possible development for topical use.”