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NutriLock™

We offer a range of lock solutions to meet the individual needs of each patient. NutriLock™ has proven particularly suitable for vascular access devices (VAD) used in cancer treatment and parenteral nutrition. Thanks to the antimicrobial agent taurolidine, it protects patients against catheter-related complications. 

Nutrilock-3ml

Indication and effect

NutriLock™ has been approved for instillation in all central-venous access systems. It prevents the formation of bacterial biofilm and thereby keeps catheters infection-free. The lock solution is recommended for catheters in parenteral nutrition.

Composition

NutriLock™ contains 2 % taurolidine. This substance has a broad antimicrobial activity against gram-positive and gram-negative bacteria (incl. MRSA and VRE) and fungi (e.g. Candida).

 

Application

In-between food intakes via parenteral nutrition or chemotherapy sessions, NutriLock™ remains in the VAD. Please note that medical staff must respect the filling volume of each catheter or port system.

Expert recommendations

 

Taurolidine-based lock solutions such as NutriLock™ are recommended in national and international guidelines. For patients receiving dialysis treatment via VAD, we recommend TauroLock™-Hep500.

Nutrilock-Ampoules-Packaging

Contraindications

We do not recommend using NutriLock™ for patients who:

  • have displayed allergic reactions to taurolidine
  • are concurrently taking medication that interferes with taurolidine

Safety

Before using the device, NutriLock™ must be aspirated with a syringe and then flush the VAD with saline. If aspiration is not feasible, slow flushing of NutriLock™ (not more than 1 ml per 3 seconds) prior to the next treatment will not

cause any systemic effect due to its active ingredient. 

Package sizes

NutriLock™ is available in 3 ml ampoules (single dose, 10 ampoules per box). Please note that you each ampoule can only be used once. 

Storage & transport

NutriLock™ must be stored at temperatures between 15 °C and 30 °C. Please note that you must not freeze the lock solution under any circumstances.

More about NutriLock

 

International guideline recommendations, e.g. ESPEN 2018:

“Recommendation R 10.25: Taurolidine is effective in preventing CRBSI and should be used during long term catheter use. (Extrapolated evidence from adult studies rated as LoE 1+, RGB, strong recommendation for)"

ESPEN recommendations for NutriLock™ in parenteral nutrition

Recommendation 34: As an additional strategy to prevent CRBSIs, taurolidine locking should be used because of its favorable safety and cost profile. Grade of Recommendation B - Strong consensus (100% agreement)

ESPEN pediatric recommendations for NutriLock™ in parenteral nutrition

Recommendation R 10.25 Taurolidine is effective in preventing CRBSI and should be used during long term catheter use (Extrapolated evidence from adult studies rated as LoE 1+, RGB, strong recommendation for)

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